A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Taxonomy:                                                                            

                                                                                                 Kingdom  : Plantae

                                                                                                 Division   : Magnoliophyta

                                                                                                 Class        : Magnoliopsida

                                                                                                  Order       : Malpighiales

                                                                            ,                     Family     : Euphorbiaceae

                                                                                                  Genus      : Croton

Chemical Constituents:

Trans-Dehydrocrotonin (t-DCTN), a 19-nor-clerodane diterpenes, diterpene lactone, dehydrocrotonin (DHC-compound I), compound II (produced by reducing the cyclohexenone moiety of DHC with NaBH(4)); compound III (produced by reducing the carbonyls with LiAlH(4)); and compound IV (produced by transforming the lactone moiety into an amide).linalool rich essential oils,trans-crotonin (CTN), cis-cajucarin B, cajucarin A, cajucarinolide and two novel clerodanes, trans-cajucarin B and sacacarin, triterpene acetyl aleuritolic acid (AAA),Three steroids (beta-sitosterol, stigmasterol and sitosterol-3-O-beta-glucoside), two flavonoids (kaempferol 3,4', 7-trimethyl ether and 3,7-dimethyl ether) and one diterpene (cajucarinolide)

 Part used : Whole plant

Reference:

             Chemical constituents:

• Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara. www.ncbi.nlm.nih.gov/pubmed/10720788
• Anti-tumour activity of two 19-nor-clerodane diterpenes, trans-dehydrocrotonin and trans-crotonin, from Croton cajucara. www.ncbi.nlm.nih.gov/pubmed/10630105  

• Comparison of the gastroprotective effect of a diterpene lactone isolated from Croton cajucara with its synthetic derivatives.   

              www.ncbi.nlm.nih.gov/pubmed/12860303

• Antimicrobial activity of Croton cajucara Benth linalool-rich essential oil on artificial biofilms and planktonic microorganisms.

             www.ncbi,nlm.nih.gov/pubmed/15720570

• Dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells HL60. www.ncbi,nlm.nih.gov/pubmed/15363588

             Anti-hyperglycemic activity:

• Blood glucose- and triglyceride-lowering effect of trans-dehydrocrotonin, a diterpene from Croton cajucara Benth., in rats.

             http://www.ncbi.nlm.nih.gov/pubmed/11903418

• Hypoglycemic effect of trans-dehydrocrotonin, a nor-clerodane diterpene from Croton cajucara.

             http://www.ncbi.nlm.nih.gov/pubmed/9434613