A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Taxonomy:                                                                            

                                                                                                 Kingdom  : Plantae

                                                                                                 Division   : Magnoliophyta

                                                                                                 Class        : Magnoliopsida

                                                                                                  Order       : Cucurbitales

                                                                            ,                     Family     : Cucurbitaceae

                                                                                                  Genus      : Momordica

Chemical Constituents:

Roots:Five cucurbitacins, kuguacins A–E, together with three known analogues, 3β,7β,25-trihydroxycucurbita-5,(23E)-diene-19-al , 3β,25-dihydroxy-5β,19-epoxycucurbita-6,(23E)-diene , and momordicine I ,lenoic acid ,lenolenic acid,

Fruits:alkaloids, glycosides, aglycone, tannin, sterol, phenol , protein, Vincine, Mycose, Momordicoside A and Momordicoside B.
Seed essential oil: Trans-nerolidol, apiole, cis-dihydrocarveol and germacrene D.

Part used : Seeds and fruit

Reference:

             Chemical constituents:

• Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia.www.ncbi.nlm.nih.gov/pubmed/18045630

• Antioxidative effect of conjugated linolenic acid in diabetic and non-diabetic blood: an in vitro study.www.ncbi.nlm.nih.gov/pubmed/17693694

• Fractionation and identification of 9c, 11t, 13t-conjugated linolenic acid as an activator of PPARalpha in bitter gourd (Momordica charantia L.)

              www.ncbi.nlm.nih.gov/pubmed/16955349

• Phytochemical determination and extraction of Momordica charantia fruit and its hypoglycemic potentiation of oral hypoglycemic drugs in diabetes mellitus (NIDDM)www.ncbi.nlm.nih.gov/pubmed/15521566

• Study on chemical components of Momordica charantia
  www.ncbi.nlm.nih.gov/pubmed/12569838

              www.ncbi.nlm.nih.gov/pubmed/2104468

• Chemical composition and antimicrobial activity of Momordica charantia seed essential oil.www.ncbi.nlm.nih.gov/pubmed/18164872

             Anti-hyperglycemic activity:

• Effect of Indian herbal hypoglycemic agents on antioxidant capacity and trace elements content in diabetic rats.www.ncbi.nlm.nih.gov/pubmed/18800899

• A cell-based screening identifies compounds from the stem of Momordica charantia that overcome insulin resistance and activate AMP-activated protein kinase.

              www.ncbi.nlm.nih.gov/pubmed/18656931

• Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway.www.ncbi.nlm.nih.gov/pubmed/18355726

• Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions.www.ncbi.nlm.nih.gov/pubmed/18321395

• Regeneration of beta cells in islets of Langerhans of pancreas of alloxan diabetic rats by acetone extract of Momordica charantia (Linn.) (bitter gourd) fruits. 

             www.ncbi.nlm.nih.gov/pubmed/18254212

• Modulatory effect of bitter gourd (Momordica charantia LINN.) on alterations in kidney heparan sulfate in streptozotocin-induced diabetic rats.

             www.ncbi.nlm.nih.gov/pubmed/18024034

• An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract.

http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=2048984&blobtype=pdf

• The effect of Momordica charantia capsule preparation on glycemic control in type 2 diabetes mellitus needs further studies.www.ncbi.nlm.nih.gov/pubmed/17493509

• Hypoglycaemic and hypotensive effects of Momordica charantia Linn (Cucurbitaceae) whole-plant aqueous extract in rats.

www.ncbi.nlm.nih.gov/pubmed/17117226

• Momordica charantia constituents and antidiabetic screening of the isolated major compounds.www.ncbi.nlm.nih.gov/pubmed/16819222

• Some toxicological studies of Momordica charantia L. on albino rats in normal and alloxan diabetic rats.

  www.ncbi.nlm.nih.gov/pubmed/16815658

• Effect of bitter gourd and spent turmeric on constituents of glycosaminoglycans in different tissues in streptozotocin induced diabetic rats.

www.ncbi.nlm.nih.gov/pubmed/16532259

• Anti-diabetic potentials of Momordica charantia and Andrographis paniculata and their effects on estrous cyclicity of alloxan-induced diabetic rats.

www.ncbi.nlm.nih.gov/pubmed/16298503