A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Taxonomy:                                                                            

                                                                                                 Kingdom  : Plantae

                                                                                                 Division   : Magnoliophyta

                                                                                                 Class        : Magnoliopsida

                                                                                                  Order       : Sapindales

                                                                            ,                     Family     : Meliaceae

                                                                                                  Genus      : Melia

Chemical Constituents:

Azharone (5,7,4'-trihydroxy-3'-(3''-methyl-2'',3''-epoxybutyl)flavan-4-one (3)) azadirone , and isoazadironolide, tetracyclic triterpenoids zafaral [24,25,26,27-tetranorapotirucalla-(apoeupha)-6alpha-methoxy-7alpha-acetoxy-1,14-dien-3,16-dione-21-al] ,meliacinanhydride [24,25,26,27-tetranorapotirucalla-(apoeupha)-6alpha-hydroxy,11alpha-methoxy-7alpha,12alpha-diacetoxy,1,14,20(22)-trien-3-one]  nimocinol and isomeldenin,di -unsaturated fatty acids, icosane, docosane, 2-methyltricosane, and docosene ,tetranortriterpenoids, azadirone, epoxyazadiradione, nimbin, gedunin, azadiradione, deacetylnimbin, and 17-hydroxyazadiradione.  protolimonoid, naheedin , azadirachtol, limonoid,Mahmoodin ,apo-tirucallol (apo-euphol) .

Part used : Whole plant, Leaves, Fruits, Flowers

Reference:

              Chemical constituents:

• A new flavanoid from the flowers of Azadirachta indica,leaves

             www.ncbi.nlm.nih.gov/pubmed/16401554

• Tetracyclic triterpenoids from the leaves of Azadirachta indica .

              www.ncbi.nlm.nih.gov/pubmed/15381008

• Constituents of Azadirachta indica: isolation and structure elucidation of a new antibacterial tetranortriterpenoid, mahmoodin, and a new protolimonoid, naheedin

www.ncbi.nlm.nih.gov/pubmed/1593280

• Studies in the Chemical Constituents of Azadirachta indica Part II: Isolation and Structure of the New Triterpenoid Azadirachtol www.ncbi.nlm.nih.gov/pubmed/17345262

              Anti-hyperglycemic activity:

• Effect of aqueous extract of neem (Azadirachta indica) leaves on offensive and diffensive gastric mucosal factors in rats.

www.ncbi.nlm.nih.gov/pubmed/17193895

• Clinical investigation of hypoglycemic effect of seeds of Azadirachta-inidca in type-2 (NIDDM) diabetes mellitus.

www.ncbi.nlm.nih.gov/pubmed/17105712

• Hypoglycaemic effects of some plant extracts are possibly mediated through inhibition in corticosteroid concentration.

www.ncbi.nlm.nih.gov/pubmed/15587591

• Lowering of blood sugar by water extract of Azadirachta indica and Abroma augusta in diabetes rats.www.ncbi.nlm.nih.gov/pubmed/15266913

• Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats.www.ncbi.nlm.nih.gov/pubmed/15088689

• Protective role of extracts of neem seeds in diabetes caused by streptozotocin in rats.

www.ncbi.nlm.nih.gov/pubmed/15013179

• A study of hypoglycaemic effects of Azadirachta indica (Neem) in normaland alloxan diabetic rabbits.

  www.ncbi.nlm.nih.gov/pubmed/10919098

• Exploration of the frontiers of tradomedical practices: basis for development of alternative medical healthcare services in developing countries.

             www.ncbi.nlm.nih.gov/pubmed/8410912

• Proceedings: Pharmacological studies on the leaves of Azadirachta indica.

              www.ncbi.nlm.nih.gov/pubmed/4156703